HTX SubliMATE™️: MALDI Imaging with Solvent-Free Matrix Deposition
The HTX SubliMATE is a robust and easy to use MALDI matrix deposition system for controlled, reproducible, sublimation of the smallest available matrix crystals for sub-micron resolution mass spectrometry imaging.
Using a fully integrated ceramic heater for consistent and quick heating, a range of MALDI matrices can be sublimated onto a maximum of 4 slides. The slides are then cooled to 15 to -78 oC to produce ultra small matrix crystals for sub-micron resolution mass spectrometry imaging.
What are the benefits of sublimation?
Improved Spatial Resolution: Sublimation provides minimum crystal size in the nanometer range.
Delocalization is minimised: By skipping the liquid phase in the matrix deposition process, more spatial information is preserved in samples.
Increased efficiency: The matrix layer can be applied in one single process before each sublimation cycle ensuring homogenous distribution of matrix crystals.
Key Features
- Four slide capacity for increased throughput
- Fast heating and cooling for quick sample preparation
- Highly consistent matrix deposition across entire sample area
- Proprietary Matrix Wafer template design for even distribution of matrix prior to sublimation
- Validated protocols for most MALDI matrices (eg. CHCA, DAN, DHAP, DHB, NEDC)
- Continuous matrix coverage as needed for high spatial resolution MALDI imaging
Discover more about the HTX SubliMATE: MALDI Imaging and Sample Prep – Verulam Scientific
Or contact Verulam Scientific to see how we can help you further.
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🌐 https://verulamscientific.com/htx-imaging-solutions/#sublimator





