HUDSON LAB AUTOMATIONRapid pH™ Plus Automated pH Meter
Discover more about our Rapid pH Plus meter from Hudson Lab Automation. Use the link below to contact a member of our team and discuss your requirements today.
Rapid pH™ Plus – Automated, Accurate Benchtop pH Measurement in Microplates and Small Vials
Rapid pH Plus is an automated, plate-based system powered by intuitive software that enables reproducible, searchable data generation for high-throughput formulation and buffer optimization workflows.
Configurable hardware supports single- or 4-probe capacity, with optional Power Wash, enabling scalable performance across diverse biologics development workflows.
Integrated Platform for Reliable pH Measurement Workflows
- Built-in controllable heated nest ensures temperature stability during measurement, critical for accurate and reproducible pH readings in protein and biologic formulations
- Integrated static, standard, and Power Wash options enable reproducible multi-sample testing in single runs
- Static wash enables decontamination using enzymatic cleaners, solvents, and degreasers
- Process samples with consistent, reproducible results and walk-away operation
Software Designed for Multi-Condition pH Optimisation
Rapid pH Plus Software provides complete control and visualization of plate-based pH measurements, from setup and experimental design to high-throughput measurement and data retrieval.
Designed around a plate-first workflow, the software allows users to set up and run a full plate in just a few clicks. Clear well selection, read-order controls, and real-time run visibility make operation simple – even for new users.
• Flexible data export to CSV, Excel, and XML for integration with downstream systems
• Built-in integration API for instrument control and data access
• User-defined wash protocols provide full control over probe cleaning
Applications
Rapid pH Plus is ideal for measuring the pH of:
- Biological samples
- Cosmetics and personal care products
- Water samples
- Pharmaceutical samples
| Model | Best For | Throughput (full 96-well plate) | Sample Complexity | Key Application Fit |
|---|---|---|---|---|
| Rapid pH Plus Single-Probe | Routine workflows, smaller studies, QC testing | ~ 1.5 hrs | Standard samples (buffers, simple formulations) | General pH measurement, medium throughput screening |
| Rapid pH Plus Single-Probe + Power Wash | Workflows with difficult or carryover-prone samples | ~ 1.5 hrs | Viscous, protein-rich or residue-forming samples | Formulation work with challenging matrices requiring enhanced cleaning |
| Rapid pH Plus 4-Probe | High throughput workflows | ~ 20 – 25 mins | Standard samples across many conditions | Large scale buffer optimisation and plate-based screening |
| Rapid pH Plus 4-Probe + Power Wash | High throughput workflows with difficult or carryover-prone samples | ~ 20 – 25 mins | Viscous, sticky, surfactant-rich or complex samples | Scalable formulation and buffer optimisation with difficult samples |
Specifications
- Unit
- Plate
- Wash & Cleaning
- Probe & Measurement
- Workflow & Run
- Data & Export
- Calibration & Tolerance
| Dimensions (W x H x D) | 380 x 330 x 380 mm |
|---|---|
| Weight | 11 kg |
| Power | 120/240 VAC; 50/60Hz |
| Air | 40-60 psi clean, dry air or N2 |
| Computer Interface | USB or Ethernet |
| Plate Formats | Supports standard 96-, 48-, and 24-well plates and other ANSI/SLAS-compatible plate formats for probe-based measurement |
|---|---|
| Rows and Columns | Fully customizable plate layouts |
| Well Spacing | Configurable X/Y spacing (mm) |
| A1 Offset | Adjustable X/Y offsets for custom plates |
| Plate Height | User-defined (max ~52 mm) |
| Read Depth | Adjustable probe depth per plate |
| Wash Methods | Fully customizable multi-step workflows |
|---|---|
| Wash Steps | Wash, dry, wait, buffer soak |
| Step Order | Drag-and-drop reordering |
| Cycle Wash | Configurable as a step (not fixed) |
| Dry Cycles | Adjustable number of air-dry cycles |
| Multiple Methods | Support for multiple saved wash protocols |
| Probe Type | Mettler Toledo InLab® Micro Probe |
|---|---|
| Probe Configurations | Available in single- and 4-probe systems (software supports scalable multi-probe configurations) |
| Multi-Read | Configurable number of reads per well |
| Read Averaging | Automatic averaging of multiple reads |
| Read Order | Row forward/reverse, column forward/reverse |
| Sample Temperature | User-defined estimate |
| Heated Nest Control | Adjustable target temperature |
| Well Selection | Click, drag, row, column, or full plate |
|---|---|
| Minimum Sample Volume | ~200 µL (typical for 96-well plates) |
| Sample Selection | Manual selection or file-based (CSV) import |
| Sample ID Integration | CSV-based mapping per well |
| Barcode Integration | External (via API or file-based integration) |
| Notes & Metadata | User-defined searchable run notes and keywords |
| Run Control | Start, pause, stop |
| Collision Detection | Sensor-based protection to prevent probe damage |
| Throughput | ~1.5 hours per 96-well plate (single-probe)<BR> ~20-25 minutes per 96-well plate (4-probe) |
| Export Formats | XML, CSV, SAM, Excel, JSON |
|---|---|
| Export Mode | Plate layout, list, read-order |
| Auto Export | Configurable export folder |
| Multi-Plate Export | Batch export capabilities |
| Clipboard Export | Copy data directly for external use |
| Data Capture | Stores individual read values with automatic calculation of mean and standard deviation |
| Calibration Points | User-defined (supports any standard buffer; common examples include pH 4, 7, 10) |
|---|---|
| Verification Wells | Optional |
| Offset Tolerance | Configurable (default ±50 mV) |
| Slope Tolerance | Configurable (default ±5%) |
| Slope Deviation | Configurable (default 5%) |
| Verification Tolerance | Configurable (default ±0.05 pH) |
| Multi-Read Tolerance | Configurable |
Why Choose Verulam Scientific?
Verulam Scientific is the UK distributor for many highly reputable US and European manufacturers, and we are committed to providing unrivalled quality on products and services. Our curated team of industry professionals have been delivering innovative solutions and reliable instruments to customers since 2009.
What Do Our Customers Say?
You can read what our past clients—including institutions like the University of Oxford, the University of Edinburgh, and Vernalis Research—have to say about their partnerships with Verulam Scientific on our Testimonials page linked below.
Rapid pH™ Plus FAQs
Can I use my own custom tray?
Custom trays are configurable in the software but they must be of SBS (standard well plate) format.
How is the Rapid pH Plus calibrated?
Rapid pH Plus calibration is built into the workflow. Calibration standards are assigned directly to wells with visual mapping of calibration points. The calibration is run within the same interface and robust calibration statistics can be quickly assessed.
My samples are viscous. Are they suitable for the Rapid pH Plus?
The Rapid pH Plus has an optional power wash which sprays the probe with wash solution to remove contamination between measurements. Power wash is suitable for viscous, sticky, surfactant-rich, protein-rich, residue-forming, or complex samples.
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