Bertin InstrumentsPrecellys Homogenisers
Conduct effective tissue homogenisation for reproducible & efficient sample preparation. Use the link below to get in touch with a member of the Verulam Scientific team and discuss your requirements today.
Effective Tissue Homogenisation for Reproducible Sample Preparation
The range of Precellys homogenisers from Bertin Health & Life Sciences provides efficient extraction of molecules such as RNA, DNA, proteins, metabolites and more. Conducting sample preparation from biological samples using Bertin homogenisers grants you access to bead-beating technology, allowing you to homogenise various biological samples, including human, animal or plant tissues, or to lyse micro-organisms.
Advanced Technology
Using multi-directional movement – also known as 3D bead-beating – biological samples are ground at a speed of up to 10,000 rotations per minute. This means that samples can be effectively homogenised within a matter of seconds. Sample molecules such as nucleic acids, proteins and metabolites can then be analysed using a range of techniques. Simplify sample preparation protocols by saving a considerable amount of time with a Bertin homogeniser.
Related Applications
The Precellys® range allows you to prepare samples in full safety and without cross-contamination, for both routine applications and R&D projects.
Available Precellys Homogenisers
Take a look below at the range of homogenisers from Bertin. Contact a member of the Verulam Scientific team to discuss your requirements.
Minilys Personal Homogeniser
Meet the sample preparation needs for laboratories analysing biological samples with the Minilys personal homogeniser. This compact, flexible homogeniser offers the ideal solution for lysing and homogenising efficiency, and optimal grinding. Minilys is capable of handling 3 x 2mL/0.5mL tubes or 1 x 7mL tube to process any type of sample. This affordable instrument provides a manual tube locking system, easy to use, ensuring it is the perfect solution for daily lab workflow. Associated with the appropriate lysing kit, Minilys can even grind difficult samples like grains or hairs.
Benefits
- Flexibility: Process either 3 x 0.5 or 2mL tubes at once or 1 x 7mL tube.
- Easy handling: With only two parameters to choose from (speed and time) the Minilys is operational immediately.
- Efficiency: Minilys is the only small homogeniser based on 3D motion that reaches 5000 rpm.
Technical Specifications
| Specification | Details |
|---|---|
| Capacity | 1 – 3 x 2ml, 0.5ml tubes |
| Speed range | 3000, 4000 & 5000 rpm |
| Locking system | Manual (no screw-in system) |
| Cycle time | 5s to 240s |
| Weight | 17lb / 7 kg |
| Dimensions | Length 180mm x Width 290mm x Height 380mm |
| Power requirement | 100 – 230 VAC / 50-60 Hz / Power 1 kVA |
| Noise | < 70 dB |
Precellys 24 Touch Homogeniser
The Precellys 24 Touch offers the perfect instrument for the homogenisation of all biological samples, regardless of origin. Validated on over 1,500 samples such as muscle, brain and heart samples, and bones, hair and seeds, the Precellys 24 Touch can treat up to 24 samples at a time. Make use of the intuitive touchscreen to control the instrument’s powerful 3D movement, with homogenisation occurring in a few seconds at speeds from 4500 to 6800 rpm. Its exclusive vacuum-based tube locking system and design ensures that the Precellys® 24 Touch is compliant with safety requirements of the harshest lab environments, such as biological safety level 3.
The Precellys® 24 Touch provides high energy to the beads contained in the tubes, ensuring samples can then be processed for further analysis amongst a wide variety of techniques dedicated to DNA/RNA (PCR, electrophoresis, NGS, chips, etc), protein (blotting, mass spectrometry, etc.), or metabolites analyses (chromatography, etc.)
Benefits
- Efficient: Powerful 3D motion, up to 6,800 rpm
- Easy to use: Touchscreen and exclusive tube locking system
- Reproducible: Validated protocols available online
- High quality: Robust, ergonomic & safe
Technical Specifications
| Specification | Details |
|---|---|
| Capacity | 1 to 24 tubes of 2 mL, 1 to 24 tubes of 0.5 mL |
| Speed range | 4,500 rpm to 6,800 rpm (by increments of 100 rpm) |
| Programs | Unlimited |
| Number of cycles | Up to 10 |
| Cycle time | Up to 90 sec |
| Pause between cycles | 120 sec |
| Weight | 23 kg / 51 lb |
| Dimensions | L: 287 mm, W: 408 mm, H: 390 mm, (515mm with opened lid) |
| Power requirement | 90 – 250VAC / 50-60 Hz, Power: 1 kVA |
| Noise | < 70 dB |
Precellys Evolution Touch Homogeniser
The Precellys Evolution Touch is Bertin’s highest-performance homogeniser, offering the most advanced technology for a wide range of sample preparation requirements. This exceptionally efficient and versatile instrument can be used for the homogenisation of any biological sample, whether human, animal, or plant, regardless of whether tissues are hard or soft. Utilising 3D bead-beating technology, reproducible, efficient sample preparation occurs with speeds of up to 10,000 rpm.
Using the Precellys® Evolution Touch, you can prepare from 1 to 96 tubes at the same time, with six different tube volumes from 0.3 to 50mL. In areas as varied as pharmacology, medical research, forensic medicine, the environment, microbiology, or agronomy, the Precellys® Evolution Touch saves you precious time in your routine and R&D projects requiring tissue homogenisation or cell disruption. This preliminary processing is crucial for proteins, drugs, metabolites, RNA or DNA extraction.
Benefits
- Efficiency on every sample: Up to 10,000 rpm to process and standardise any sample preparation in seconds.
- Easy handling: The innovative and patented automatic tube locking system allows for easy handling of the Precellys Evolution Touch without advanced training.
- Adapted to any type of sample: The high flexibility of the Precellys Evolution Touch, which is capable of handling four sizes of tube (0.5, 2, 7, 15 and 50 mL), makes it the perfect tool when processing samples of different sizes, weight or volume.
- Protection for thermo-sensitive molecules: The Precellys Evolution Touch is compatible with the Cryolys Evolution cooling unit. This combination allows users to protect sensitive molecules when processing samples.
Technical Specifications
| Specification | Details |
|---|---|
| Capacity | 8 to 96 wells, 300µL 1 to 24 tubes, 2mL/0.5mL 1 to 12 tubes, 7mL 1 to 6 tubes, 15mL 1 to 3 tubes, 50mL 1 to 6 metal tubes |
| Speed range | 4,500 rpm to 10,000 rpm (increment by 100 rpm) |
| Locking System | Automatic tubes locking system – patented |
| Programs | The software allows users to save an unlimited number of protocols |
| Number of cycles | Up to 10 |
| Cycle time | Up to 90 sec (increment by 1sec) |
| Weight | 60lb / 27kg |
| Dimensions | L: 378mm, W: 515mm, H: 400mm (632mm with open lid) |
| Power requirement | 90 – 250VAC / 50-60 Hz, Power: 1 kVA |
| Noise | < 70 dB |
Effective Cooling System
Prevent Thermo-Sensitive Samples from Heat Degradation with the Cryolys Evolution, available for purchase separately. Compatible with the Precellys Evolution tissue homogeniser, the Cryolys Evolution uses dry ice sublimation to enhance the efficiency of molecular extraction. This subsequently improves the quality of analysis, ensuring the optimal temperature between 0 and 10°C is maintained before and during tissue homogenisation.
The Cryolys Evolution unit must run off Precellys Evolution, as the Precellys Evolution tissue homogeniser software monitors the temperature for fully accurate results. It allows an optimal protection of the sensitive molecules from heat degradation. Cryolys Evolution is the ideal solution when working on native state thermo-sensitive molecules such as active RNA, siRNA, metabolites, enzymes, and proteins while getting a high yield extraction.
Benefits
- Easy to install: Powered and controlled by Precellys Evolution, no compressed air required.
- Easy to use: Precellys Evolution software automatically monitors the protocol run.
- Fast and accurate: Target temperature reached in less than two minutes and fully monitored.
Technical Specifications
| Specification | Details |
|---|---|
| Capacity | 1,5kg/3,3lb of dry ice |
| Space requirement | Height over bench: 70cm Depth of the bench: 70cm |
| Dry ice consumption | 1,5kg/3,3lb for 30 min (run time) |
| Weight | Full unit: 2,6kg/5,7lb Detachable cooling module: 1,3kg/2,8lb |
| Dimensions | L: 335mm, W: 335mm, H: 100mm |
| Requirement | Unit plugged to a Precellys Evolution |
| Noise | < 60 dB |
What Our Customers Say
Over the years, we have had the privilege of working with a number of highly-respected UK institutions. Click the link below to take a look at what some of our previous clients have to say about a partnership with Verulam Scientific.
We were in need for MALDI matrix sprayer for new MADLI imaging capacity in my lab. Verulam Scientific recommended spray form Mass Spec manufacturer.. this was delivered on time and in budget. Dr. Andrew Reeder was extremely kind and professional especially when installation needed to be delayed significantly. I would highlight the great guidance when discussing options with a novice (me) in the field and definitely the flexibility re installation and service arrangements.
Roman Fischer - Associate Professor, University of Oxford
Why Choose Verulam Scientific?
At Verulam Scientific, we have specialisms in a number of fields, including chromatography, electrochemistry, MALDI imaging, and laboratory automation. We are also proud to be the UK distributors for highly reputable European and US manufacturers, providing bespoke solutions for our customers. Learn more about how we operate by using the link below.
Contact Us
If you would like further information on Precellys or would like to request a demonstration, please fill in the form below and one of the team will be in touch.
Precellys Homogenisers FAQs
Should I Add Liquid Or Lysis Buffer To The Tube Before Starting The Homogenisation Process?
You should generally add the lysis buffer to the tube before starting the homogenisation process. Adding the lysis buffer first (or simultaneously with the sample) ensures immediate stabilisation of the biological components, protects them from degradation by endogenous enzymes (such as RNases or proteases), and increases yield.
How Can I Prevent Heat Generation And Protect Thermo-Sensitive Molecules (Like RNA Or Proteins)?
Preventing heat generation and protecting thermo-sensitive molecules like RNA and proteins requires a combination of strict temperature management, the use of stabilising additives, and careful handling techniques to minimise denaturation and degradation.
Can The Precellys Homogeniser Effectively Grind Very Hard Materials Like Bone, Teeth, Or Seeds?
Yes, the Precellys Touch homogenisers are highly effective at grinding very hard materials such as bone, teeth, and tough seeds. They utilise high-speed 3D bead-beating technology—reaching up to 10,000 rpm—to grind these materials in a short period of time (typically 30-60 seconds).
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