Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathy (BSE) or its human form, the New Variant of Creutzfeldt-Jakob disease. This antibody recognises the octo-repeat region located in the N-terminal part of PrP.

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