Focus of the MonthMALDI Imaging M3+ Sprayer
The M3+ Sprayer from HTX Technologies is a fully automated MALDI matrix deposition instrument offering robustness, ease of use, and time-saving automation that will meet the demanding needs of MALDI Imaging Mass Spectrometry Labs.
The HTX M3+ Sprayer is based on a patented spray nozzle design. The unique combination of heat (the nozzle can be temperature controlled up to 140 C), pressure (carrier solvent is delivered at high pressure by an isocratic pump) and drying sheath gas (Dry Air or Nitrogen) results in a precisely controlled solvent/matrix deposition that can be used for many matrix types.
This unique ability to control liquid and propulsion gas temperature creates a fine solution mist that is wet enough to maximize analyte extraction, yet warm enough to evaporate quickly before delocalization takes place. This ensures both high signal and the best spatial resolution.
Key Benefits
An 8-way valve and smart PumpScripts integrates priming, flushing, and washing steps into any protocol, ensuring that the instrument maintains optimum performance over time, and is left contaminant-free for the next user.
HTX is the only sample preparation system available that allows users to heat the matrix solution as it is being applied to their sample. ensures a very fine, uniform and reproducible
matrix coating crucial for high spatial resolution imaging and relative quantification of
analytes.
The fully redesigned User Interface greatly simplifies training, everyday use, and switching between protocols, users, and projects.
- Suitable for Multi-User Facilities
The software user interface facilitates training of new users who can safely operate the instrument within minutes. Flushing and washing protocols are fully automated and attached to each method which ensures that the instrument is always left perfectly cleaned and ready for the next user at the end of a cycle.
Many imaging workflows require multiple spray methods and thorough cleaning between consecutive spray cycles of enzyme, internal standards, or derivitisation reagents prior to matrix application. This would normally require modifying the instrument configuration. However, due to the automated valve of the HTX M3+ sprayer multi reagents and cleaning solvents can be selected automatically. The instrument also fully handles any complex
cleaning though the embedded PumpScripts™.
Discover more about the HTX sample prep maldi imaging sprayers: MALDI Imaging and Sample Prep – Verulam Scientific
Or contact the Verulam Scientific team on 01234 381000 or email [email protected]
